At the central control, Leo fights the Giant Mouser. Leo then invades the laboratory, which has been overran by Ninjas. Leonardo drives the Sewer Slider to arrive into Stocktronic Industries from underground. April reveals that the Mousers are a part of an evil plan by her boss, Baxter Stockman, so the Turtles decide to stop him. Afterwards, Leonardo goes further into the sewers, where he saves April O'Neil.

Shortly after a group of Mousers destroy the Turtles' old home, they begin to attack their new home. Once all four levels are completed, the Turtles strike on the Foot Headquarters, where they fight Hun before going after the Foot leader, The Shredder. Afterward, they are confronted by genetically mutated beings. Afterwards Stockman develops for the Foot Clan invisible Foot Tech Ninjas to capture Raphael, forcing the Turtles to rescue them and Donatello to use a cloaking device detector to properly fight the invisible ninjas. At the surface, he is confronted by Purple Dragons' thugs, and meets Casey Jones, who equally hates that gang. Afterwards Michelangelo gets on Raphael's nerves, making Raphael leave to the surface. Eventually the Turtles trace the robots back to Baxter Stockman's factory, where they save young April O'Neil. Shortly after a group of Mouser Robots destroy the Turtles' old home, they begin to attack their new home. Raphael uses his sai to climb walls and has a motorcycle racing minigame riding the Shell Cycle against Casey Jones. Donatello climbs pipes and has a shoot 'em up level using a hang glider. Michelangelo can wall jump, and rides a skateboard through sewers. Leonardo can crawl through small spaces and rides the hovercraft Sewer Slider for a rail shooter minigame. After the player chooses one of the Ninja Turtles, each of whom has a special ability, the character enters a set of four acts, one of which is a vehicle-riding minigame. Teenage Mutant Ninja Turtles is a regular beat 'em up platform game.

Download TMNT (Game Boy Advance)